OTS964

Product Name: OTS964
CAS No.: 1338545-07-5
Chemical Name: OTS964
Synonyms: OTS964;CS-2531;OTS964 HCl;OTS964; OTS 964;OTS964+OTS964 HCl;OTS964 HYDROCHLORIDE;(R)-9-(4-(1-(dimethylamino)propan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one;(R)-9-[4-[1-(Dimethylamino)propan-2-yl]phenyl]-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one Hydrochloride
CBNumber: CB02737339
Molecular Formula: C23H24N2O2S
Formula Weight: 392.51386
MOL File: 1338545-07-5.mol

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OTS964 Property

storage temp.: Store at -20°C
solubility: ≥88.6 mg/mL in DMSO; ≥2.15 mg/mL in EtOH with gentle warming and ultrasonic; ≥2.1 mg/mL in H2O with gentle warming and ultrasonic
form: crystalline solid

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Safety

HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 17052
Product name: OTS964 (hydrochloride)
Packaging: 1mg
Price: $92
Updated: 2024/03/01

Cayman Chemical

Product number: 17052
Product name: OTS964 (hydrochloride)
Packaging: 5mg
Price: $168
Updated: 2024/03/01

Cayman Chemical

Product number: 17052
Product name: OTS964 (hydrochloride)
Packaging: 500μg
Price: $49
Updated: 2024/03/01

TRC

Product number: O712970
Product name: OTS964
Packaging: 25mg
Price: $1175
Updated: 2021/12/16

TRC

Product number: O712970
Product name: OTS964
Packaging: 10mg
Price: $590
Updated: 2021/12/16

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OTS964 Chemical Properties,Usage,Production

Description

OTS964 is an inhibitor of lymphokine-activated killer T cell-originated protein kinase (TOPK; IC₅₀ = 28 nM). It specifically blocks cytokinesis, leading to apoptosis, in a broad range of cancer cells. OTS964 induces apoptosis of human lung cancer cells in mouse xenografts.

Uses

OTS 964 works through cytokinesis and is an effective TOPK inhibitor which has been shown to cause tumor suppression in xenografts of human cancer.

References

1. matsuo y, park jh2, miyamoto t, et al. topk inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis. ci transl med. 2014 oct 22;6(259):259ra145.

OTS964 Preparation Products And Raw materials

Raw materials

Preparation Products

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OTS964 Suppliers

China 80 India 1 United States 12 Global 93

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4662
Advantage: 60

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6393
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57511
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354
Email: support@targetmol.com
Country: United States
ProdList: 19973
Advantage: 58

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9926
Advantage: 65

1338545-07-5, OTS964Related Search:

CP 31398 Olaparib CP-31398 Dihydrochloride Hydrate

OTS964

(R)-9-[4-[1-(Dimethylamino)propan-2-yl]phenyl]-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one Hydrochloride

(R)-9-(4-(1-(dimethylamino)propan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one

OTS964 HYDROCHLORIDE

OTS964; OTS 964

CS-2531

OTS964 HCl

OTS964+OTS964 HCl

1338545-07-5

C23H24N2O2SHCl

API